Basic Information
ID: ALA2427227
Type: Binding
Description: Agonist activity at TLR7-mediated IFNalpha production in human PBMC assessed as minimum concentration of compound necessary to generate >3 fold of cytokine levels relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2427227
MEC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 424.55 | 3.18 | 3.18 |
| 422.53 | 2.79 | 2.79 |
| 408.55 | 3.35 | 3.35 |
| 426.59 | 3.51 | 3.51 |
| 409.54 | 2.83 | 2.83 |
| 411.51 | 1.67 | 1.67 |
| 412.49 | 1.64 | 1.64 |
| 486.62 | 4.46 | 4.46 |
| 486.62 | 4.46 | 4.46 |
| 439.56 | 2.62 | 2.62 |
| 424.55 | 2.96 | 2.96 |
| 424.55 | 2.96 | 2.96 |
| 424.55 | 3.18 | 3.18 |
| 426.52 | 2.03 | 2.03 |
| 410.52 | 2.79 | 2.79 |
| 410.52 | 2.79 | 2.79 |
| 327.39 | 2.20 | 2.20 |
| 424.55 | 3.18 | 3.18 |
| 410.52 | 2.79 | 2.79 |
| 396.50 | 2.52 | 2.52 |
| 499.62 | 4.16 | 4.16 |
| 411.51 | 2.24 | 2.24 |
| 499.62 | 4.16 | 4.16 |
| 423.52 | 2.49 | 2.49 |
| 409.53 | 3.40 | 3.40 |
| 423.52 | 2.49 | 2.49 |
| 451.53 | 1.19 | 1.19 |
| 409.53 | 3.40 | 3.40 |
| 424.51 | 1.88 | 1.88 |
| 423.52 | 1.92 | 1.92 |
| 426.48 | 0.73 | 0.73 |
| 424.51 | 1.89 | 1.89 |
| 424.55 | 2.83 | 2.83 |
| 424.55 | 2.83 | 2.83 |
| 410.52 | 2.81 | 2.81 |
| 436.56 | 3.32 | 3.32 |
| 422.53 | 2.72 | 2.72 |
| 424.55 | 3.18 | 3.18 |
| 424.55 | 3.18 | 3.18 |
| 437.55 | 2.10 | 2.10 |
| 452.56 | 2.42 | 2.42 |
| 438.58 | 3.43 | 3.43 |
| 450.59 | 3.57 | 3.57 |
| 444.54 | 3.19 | 3.19 |
| 424.55 | 3.18 | 3.18 |
| 410.52 | 2.65 | 2.65 |