Assay Report Card

Basic Information

ID: ALA2427514

Type: Functional

Description: Antitumor activity against human PC9 cells harboring EGFR exon 19 deletion activating mutant xenografted in SCID mouse assessed as tumor growth inhibition at 6.25 mg/kg/day, po after 7 days relative to vehicle-treated control

Organism: Homo sapiens

Cell type: PC-9

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
446.914.284.28