Basic Information
ID: ALA2427712
Type: Binding
Description: Selectivity ratio of IC50 for wild type EGFR phosphorylation in human LoVo cells over IC50 for EGFR L858R/T970M double mutant phosphorylation in human NCI-H1975 cells
Organism: Homo sapiens
Cell type: NCI-H1975
Activity Charts
Bioactivity
Activity Types for Assay ALA2427712
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 393.44 | 3.41 | 3.41 |
| 446.91 | 4.28 | 4.28 |
| 485.95 | 4.39 | 4.39 |
| 494.98 | 4.55 | 4.55 |
| 469.95 | 5.16 | 5.16 |
| 519.01 | 4.07 | 4.07 |
| 484.56 | 3.42 | 3.42 |
| 518.02 | 4.91 | 4.91 |
| 483.58 | 4.25 | 4.25 |
| 389.85 | 5.15 | 5.15 |
| 419.87 | 5.16 | 5.16 |
| 389.85 | 5.15 | 5.15 |
| 445.91 | 5.11 | 5.11 |
| 432.87 | 4.88 | 4.88 |
| 420.86 | 4.32 | 4.32 |
| 476.97 | 5.09 | 5.09 |
| 477.96 | 4.25 | 4.25 |
| 443.51 | 3.60 | 3.60 |
| 461.50 | 3.74 | 3.74 |
| 457.54 | 3.91 | 3.91 |
| 505.60 | 3.34 | 3.34 |