Basic Information
ID: ALA2429336
Type: Binding
Description: Inhibition of JNK in human SW1353 cells assessed as inhibition of TNFalpha-induced c-Jun phosphorylation incubated for 30 mins prior to TNFalpha induction measured after 20 mins
Organism: Homo sapiens
Cell type: SW1353
Activity Charts
Bioactivity
Activity Types for Assay ALA2429336
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 445.55 | 2.34 | 2.34 |
| 555.70 | 3.19 | 3.19 |
| 541.67 | 2.80 | 2.80 |
| 569.73 | 3.84 | 3.84 |
| 575.68 | 4.46 | 4.46 |
| 543.67 | 3.78 | 3.78 |
| 527.69 | 4.07 | 4.07 |
| 486.64 | 3.98 | 3.98 |
| 487.63 | 3.37 | 3.37 |
| 431.52 | 1.95 | 1.95 |
| 460.56 | 1.85 | 1.85 |
| 399.45 | 1.26 | 1.26 |
| 367.45 | 3.32 | 3.32 |
| 383.45 | 2.29 | 2.29 |
| 339.40 | 2.54 | 2.54 |
| 308.38 | 3.34 | 3.34 |
| 310.40 | 2.89 | 2.89 |
| 309.37 | 2.74 | 2.74 |
| 309.37 | 2.53 | 2.53 |
| 308.38 | 3.14 | 3.14 |
| 310.36 | 1.90 | 1.90 |
| 309.37 | 2.51 | 2.51 |
| 407.48 | 2.04 | 2.04 |
| 391.48 | 2.80 | 2.80 |
| 351.41 | 2.07 | 2.07 |
| 309.38 | 1.89 | 1.89 |
| 416.51 | 1.33 | 1.33 |
| 310.36 | 1.93 | 1.93 |
| 387.47 | 1.48 | 1.48 |
| 294.36 | 2.96 | 2.96 |