Basic Information
ID: ALA2429337
Type: Binding
Description: Inhibition of human recombinant CDK2/GST-tagged cyclin E expressed in baculovirus infected insect cells assessed as inhibition of 6XHis-tagged retinoblastoma protein (386 to 928) phosphorylation after 30 mins by scintillation counting analysis in presence of [gamma-33P]-ATP
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2429337
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.48 | 2.04 | 2.04 |
| 391.48 | 2.80 | 2.80 |
| 351.41 | 2.07 | 2.07 |
| 309.38 | 1.89 | 1.89 |
| 416.51 | 1.33 | 1.33 |
| 310.36 | 1.93 | 1.93 |
| 387.47 | 1.48 | 1.48 |
| 294.36 | 2.96 | 2.96 |