Basic Information
ID: ALA2433135
Type: Functional
Description: Antimalarial activity against sporozoite stage of Plasmodium yoelii assessed as invasion of human HepG2 cells expressing CD81 incubated for 2 hrs prior to inoculation measured after 1 hr by immunofluorescence assay in presence of penicillin/streptomycin
Organism: Plasmodium yoelii
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA2433135
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 248.72 | 2.52 | 2.52 |
| 259.35 | 2.78 | 2.78 |
| 518.06 | 6.09 | 6.09 |
| 463.50 | 5.91 | 5.91 |
| 384.43 | 2.60 | 2.60 |
| 366.84 | 5.51 | 5.51 |
| 284.35 | 2.19 | 2.19 |
| 319.86 | 2.50 | 2.50 |
| 298.38 | 2.84 | 2.84 |
| 552.46 | 6.19 | 6.19 |
| 411.46 | 3.61 | 3.61 |
| 396.88 | 2.07 | 2.07 |