Basic Information
ID: ALA2434053
Type: Binding
Description: Inhibition of ADAM-17 in human A2774 cells assessed as inhibition of EGF-induced sALCAM release incubated for 30 mins prior to EGF induction measured after 18 hrs by ELISA
Organism: Homo sapiens
Cell type: A2774
Activity Charts
Bioactivity
Activity Types for Assay ALA2434053
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 475.52 | 1.56 | 1.56 |
| 494.16 | 2.57 | 2.57 |
| 671.36 | 4.26 | 4.26 |
| 685.39 | 4.65 | 4.65 |
| 594.28 | 2.39 | 2.39 |