Basic Information
ID: ALA2434103
Type: Binding
Description: Inhibition of N-terminal 6-his tagged HCV isolate Con1 NS5B5 polymerase containing 21-amino acid deletion at C-terminus expressed in Escherichia coli using radiolabeled UTP as substrate after 2 hrs by scintillation counting analysis
Organism: Hepatitis C virus
Strain: Con1
Activity Charts
Bioactivity
Activity Types for Assay ALA2434103
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 257.33 | 3.35 | 3.35 |
| 469.56 | 3.58 | 3.58 |
| 453.56 | 4.28 | 4.28 |
| 454.55 | 3.68 | 3.68 |
| 470.57 | 5.03 | 5.03 |
| 487.02 | 5.54 | 5.54 |
| 466.60 | 5.20 | 5.20 |
| 466.60 | 5.20 | 5.20 |
| 468.58 | 3.86 | 3.86 |
| 466.56 | 3.88 | 3.88 |
| 461.63 | 4.89 | 4.89 |
| 470.98 | 4.82 | 4.82 |
| 488.97 | 4.96 | 4.96 |
| 454.59 | 4.50 | 4.50 |
| 454.59 | 4.50 | 4.50 |
| 469.56 | 3.97 | 3.97 |
| 475.61 | 3.39 | 3.39 |
| 461.63 | 3.30 | 3.30 |
| 461.63 | 2.90 | 2.90 |
| 456.56 | 4.30 | 4.30 |
| 452.58 | 4.89 | 4.89 |
| 466.60 | 4.99 | 4.99 |
| 467.55 | 4.53 | 4.53 |
| 494.57 | 4.49 | 4.49 |
| 453.56 | 4.28 | 4.28 |
| 453.56 | 4.28 | 4.28 |