Assay Report Card

Basic Information

ID: ALA2437525

Type: Binding

Description: Inhibition of TGFbeta-induced downstream transcriptional activation of ALK5 (unknown origin) expressed in CHO-HIR cells assessed as intracellular translocation of EGFP-Smad2 at 30 uM after 2 hrs by luciferase assay

Organism: Homo sapiens

Cell type: CHO-HIR

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
393.453.183.18
351.363.153.15
309.332.462.46
438.443.773.77