Basic Information
ID: ALA2437532
Type: Binding
Description: Inhibition of TGFbeta-induced downstream transcriptional activation of ALK5 (unknown origin) expressed in CHO-HIR cells assessed as intracellular translocation of EGFP-Smad2 at 1 uM after 2 hrs by luciferase assay
Organism: Homo sapiens
Cell type: CHO-HIR
Activity Charts
Bioactivity
Activity Types for Assay ALA2437532
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.40 | 3.63 | 3.63 |
| 380.41 | 4.51 | 4.51 |
| 398.42 | 3.74 | 3.74 |
| 463.52 | 3.23 | 3.23 |
| 409.45 | 4.46 | 4.46 |
| 427.46 | 3.68 | 3.68 |
| 322.32 | 2.07 | 2.07 |
| 308.34 | 2.43 | 2.43 |
| 393.45 | 3.18 | 3.18 |
| 421.46 | 2.51 | 2.51 |
| 427.46 | 4.29 | 4.29 |
| 351.37 | 2.14 | 2.14 |
| 351.36 | 3.15 | 3.15 |
| 309.33 | 2.46 | 2.46 |
| 438.44 | 3.77 | 3.77 |