Basic Information
ID: ALA2437634
Type: ADME
Description: Time-dependent inhibition of CYP3A4 in human liver microsomes assessed as midazolam hydroxylation by LC-MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2437634
Kinact
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 603.14 | 2.25 | 2.25 |
| 587.14 | 2.55 | 2.55 |
| 564.06 | 1.23 | 1.23 |
| 577.11 | 0.98 | 0.98 |
| 664.19 | 2.30 | 2.30 |
| 628.15 | 2.13 | 2.13 |
| 612.15 | 2.43 | 2.43 |
| 550.06 | 3.10 | 3.10 |
| 534.06 | 3.40 | 3.40 |
| 588.67 | 3.94 | 3.94 |