Basic Information
ID: ALA2437796
Type: Binding
Description: Inhibition of PTP1B (unknown origin) expressed in CHO cells over-expressing human IR assessed as increase in insulin-mediated IR-beta phosphorylation preincubated for 2 hrs followed by insulin challenge for 10 mins by Western blotting analysis
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2437796
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 572.77 | 7.62 | 7.62 |
| 544.72 | 7.14 | 7.14 |
| 586.80 | 7.92 | 7.92 |
| 628.88 | 8.81 | 8.81 |
| 648.87 | 9.28 | 9.28 |
| 620.82 | 8.80 | 8.80 |
| 720.85 | 8.85 | 8.85 |
| 738.84 | 8.99 | 8.99 |