Basic Information
ID: ALA2438199
Type: Functional
Description: Antagonist activity at human OX1 receptor expressed in CHO cells assessed as inhibition of orexin A-induced Ca2+ accumulation after 1 hr by Fluo-4-AM staining-based FLIPR assay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2438199
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.50 | 3.83 | 3.83 |
| 444.58 | 3.90 | 3.90 |
| 445.57 | 3.30 | 3.30 |
| 431.54 | 3.29 | 3.29 |
| 430.56 | 3.89 | 3.89 |
| 404.52 | 3.38 | 3.38 |
| 404.52 | 3.38 | 3.38 |
| 433.56 | 3.99 | 3.99 |
| 417.56 | 3.99 | 3.99 |
| 405.50 | 3.38 | 3.38 |
| 403.53 | 3.98 | 3.98 |
| 389.50 | 3.68 | 3.68 |
| 375.48 | 3.37 | 3.37 |
| 375.48 | 3.37 | 3.37 |
| 425.54 | 4.52 | 4.52 |
| 425.54 | 4.52 | 4.52 |
| 414.51 | 4.86 | 4.86 |
| 403.53 | 4.13 | 4.13 |
| 425.54 | 4.66 | 4.66 |
| 425.54 | 4.66 | 4.66 |
| 414.55 | 4.80 | 4.80 |
| 386.50 | 4.04 | 4.04 |
| 386.50 | 4.18 | 4.18 |