Basic Information
ID: ALA2438451
Type: Binding
Description: Inhibition of human recombinant ADAMTS-5 using ARGSVILTV-KPIFEVSPSPL(biotinyl)K as substrate incubated 10 mins prior to substrate addition measured after 3 hrs by spectrophotometry
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2438451
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.84 | 2.41 | 2.41 |
| 392.91 | 2.49 | 2.49 |
| 423.97 | 4.29 | 4.29 |
| 417.96 | 3.58 | 3.58 |
| 405.95 | 3.58 | 3.58 |
| 449.96 | 5.54 | 5.54 |
| 424.95 | 4.62 | 4.62 |
| 412.00 | 4.31 | 4.31 |
| 439.97 | 4.42 | 4.42 |
| 367.95 | 4.20 | 4.20 |
| 271.43 | 2.25 | 2.25 |
| 417.54 | 2.31 | 2.31 |
| 415.56 | 3.53 | 3.53 |
| 423.63 | 5.14 | 5.14 |
| 425.00 | 3.76 | 3.76 |
| 413.59 | 4.46 | 4.46 |
| 408.52 | 3.22 | 3.22 |
| 393.55 | 3.32 | 3.32 |
| 363.53 | 3.31 | 3.31 |
| 397.97 | 3.96 | 3.96 |
| 431.52 | 4.33 | 4.33 |
| 391.92 | 3.24 | 3.24 |
| 367.86 | 1.50 | 1.50 |
| 377.90 | 2.85 | 2.85 |
| 363.87 | 2.46 | 2.46 |
| 350.83 | 1.81 | 1.81 |
| 425.94 | 4.08 | 4.08 |
| 425.94 | 4.08 | 4.08 |
| 424.96 | 4.11 | 4.11 |
| 395.92 | 4.32 | 4.32 |
| 454.00 | 4.86 | 4.86 |
| 452.97 | 3.88 | 3.88 |
| 436.49 | 3.34 | 3.34 |
| 441.56 | 4.58 | 4.58 |
| 441.56 | 4.58 | 4.58 |
| 467.59 | 5.09 | 5.09 |
| 497.62 | 5.01 | 5.01 |
| 421.52 | 3.44 | 3.44 |
| 460.39 | 4.73 | 4.73 |
| 460.39 | 4.73 | 4.73 |
| 425.94 | 4.08 | 4.08 |
| 425.94 | 4.08 | 4.08 |
| 459.49 | 4.45 | 4.45 |
| 391.50 | 3.43 | 3.43 |
| 409.49 | 3.57 | 3.57 |
| 425.94 | 4.08 | 4.08 |