Basic Information
ID: ALA2438455
Type: ADME
Description: Inhibition of CYP3A4 in human liver microsomes assessed as terfenadine hydroxylation after 20 mins by LC/MS/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2438455
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 337.35 | 1.12 | 1.12 |
| 440.50 | 0.64 | 0.64 |
| 461.47 | 1.09 | 1.09 |