Basic Information
ID: ALA2439048
Type: Binding
Description: Antagonist activity at Beta-catenin/TCF in rat IEC-6 cells assessed as inhibition of Wnt-3a-induced axin2 expression preincubated for 6 hrs followed by Wnt-3a induction measured after 12 hrs by qPCR analysis
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: IEC-6
Target: Unchecked(ALA612545)
Document: ALA2434910
Antagonist activity at Beta-catenin/TCF in rat IEC-6 cells assessed as inhibition of Wnt-3a-induced axin2 expression preincubated for 6 hrs followed by Wnt-3a induction measured after 12 hrs by qPCR analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2439048
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 790.77 | 6.98 | 6.98 |
| 193.17 | -1.63 | -1.63 |
| 312.32 | 3.66 | 3.66 |
| 303.71 | 0.69 | 0.69 |
| 299.29 | 0.05 | 0.05 |
| 446.51 | 2.21 | 2.21 |
| 361.36 | 1.50 | 1.50 |