Assay Report Card

Basic Information

ID: ALA2439457

Type: Functional

Description: In vivo inhibition of XIAP BIR2 domain in human LOX cells xenografted in nude mouse assessed as potentiation of conatumumab-induced caspase 3/7 activity at 200 mg/kg, po after 8 hrs by Western blot analysis

Organism: Mus musculus

Cell type: LOX

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
534.063.403.40