Basic Information
ID: ALA2439686
Type: Functional
Description: Agonist activity at human TGR5 expressed in HEK293 cells assessed CRE-induced luciferase activity after 5.5 hrs by reporter gene assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2439686
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 450.66 | 4.33 | 4.33 |
| 484.37 | 5.85 | 5.85 |
| 486.39 | 5.93 | 5.93 |
| 588.53 | 7.02 | 7.02 |
| 512.83 | 6.06 | 6.06 |
| 410.36 | 6.08 | 6.08 |
| 428.35 | 6.22 | 6.22 |
| 442.38 | 6.78 | 6.78 |
| 456.40 | 7.17 | 7.17 |
| 453.36 | 6.28 | 6.28 |
| 435.37 | 6.14 | 6.14 |
| 471.35 | 6.42 | 6.42 |
| 478.39 | 5.40 | 5.40 |
| 496.38 | 5.54 | 5.54 |
| 495.44 | 7.40 | 7.40 |
| 533.45 | 7.79 | 7.79 |
| 568.51 | 7.32 | 7.32 |
| 582.50 | 6.96 | 6.96 |
| 572.46 | 6.55 | 6.55 |
| 452.40 | 6.33 | 6.33 |
| 466.43 | 6.73 | 6.73 |
| 514.47 | 7.63 | 7.63 |
| 548.91 | 8.28 | 8.28 |
| 515.46 | 7.02 | 7.02 |
| 504.43 | 7.22 | 7.22 |
| 504.43 | 7.22 | 7.22 |
| 520.50 | 7.69 | 7.69 |
| 520.50 | 7.69 | 7.69 |
| 522.42 | 7.36 | 7.36 |
| 518.46 | 7.78 | 7.78 |
| 532.48 | 8.17 | 8.17 |