Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of dextromethorphan metabolism by HPLC/MS analysis

Basic Information

ID: ALA2439898

Type: ADME

Description: Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of dextromethorphan metabolism by HPLC/MS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 3A4(ALA340)

Document:  ALA2434948

Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of dextromethorphan metabolism by HPLC/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
377.403.293.29
421.555.135.13
399.455.405.40
325.384.364.36
376.423.903.90
326.363.753.75