Basic Information
ID: ALA2439900
Type: ADME
Description: Inhibition of CYP2D6 in human liver microsomes assessed as inhibition of diclofenac metabolism by HPLC/MS analysis
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2439900
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.40 | 3.29 | 3.29 |
| 421.55 | 5.13 | 5.13 |
| 399.45 | 5.40 | 5.40 |
| 325.38 | 4.36 | 4.36 |
| 376.42 | 3.90 | 3.90 |
| 326.36 | 3.75 | 3.75 |