Basic Information
ID: ALA2443556
Type: Binding
Description: Inhibition of human DNA topoisomerase 2alpha-mediated relaxation of supercoiled pRYG plasmid DNA assessed as formation of linearized DNA at 100 uM after 30 mins by agarose gel electrophoresis relative to vehicle-treated control in presence of ethidium bromide
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2443556
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 283.33 | 1.58 | 1.58 |
| 344.41 | 3.66 | 3.66 |
| 389.41 | 3.57 | 3.57 |
| 374.44 | 3.67 | 3.67 |
| 360.41 | 3.37 | 3.37 |
| 412.41 | 4.68 | 4.68 |
| 359.43 | 3.25 | 3.25 |