Basic Information
ID: ALA2444340
Type: Binding
Description: Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as inhibition of [14C]-AMG uptake up to 120 mins by scintillation counting method
Organism: Homo sapiens
Cell type: CHO-K1
Activity Charts
Bioactivity
Activity Types for Assay ALA2444340
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 436.41 | -0.20 | -0.20 |
| 388.46 | 1.50 | 1.50 |
| 386.49 | 2.22 | 2.22 |
| 372.46 | 1.66 | 1.66 |
| 438.90 | 1.85 | 1.85 |
| 436.93 | 2.58 | 2.58 |
| 422.91 | 2.02 | 2.02 |
| 394.85 | 1.45 | 1.45 |
| 394.85 | 1.45 | 1.45 |
| 394.85 | 1.45 | 1.45 |
| 420.93 | 2.74 | 2.74 |
| 382.82 | 1.58 | 1.58 |
| 410.92 | 2.17 | 2.17 |
| 456.92 | 3.24 | 3.24 |
| 444.91 | 2.61 | 2.61 |
| 408.83 | 1.17 | 1.17 |
| 408.88 | 1.84 | 1.84 |
| 406.91 | 2.57 | 2.57 |