Basic Information
ID: ALA2444392
Type: Binding
Description: Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preincubated for 30 mins followed by ATP and eIF2alpha addition measured after 1 hr by HTRF assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2444392
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 451.45 | 4.37 | 4.37 |
| 384.44 | 2.74 | 2.74 |
| 384.44 | 2.74 | 2.74 |
| 384.44 | 2.74 | 2.74 |
| 398.47 | 3.05 | 3.05 |
| 416.46 | 3.19 | 3.19 |
| 452.44 | 3.76 | 3.76 |
| 470.43 | 3.90 | 3.90 |
| 387.45 | 2.31 | 2.31 |
| 387.45 | 2.31 | 2.31 |
| 401.47 | 2.62 | 2.62 |
| 419.46 | 2.76 | 2.76 |