Basic Information
ID: ALA2444633
Type: Binding
Description: Inhibition of MMP8 catalytic domain (unknown origin) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 as substrate incubated for 30 mins prior to substrate addition measured after 2 to 4 hrs by fluorometric assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2444633
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 343.21 | 2.40 | 2.40 |
| 343.21 | 2.40 | 2.40 |
| 318.61 | 2.07 | 2.07 |
| 336.00 | 2.04 | 2.04 |
| 346.01 | 1.50 | 1.50 |
| 312.11 | 0.65 | 0.65 |
| 317.17 | 1.89 | 1.89 |
| 359.21 | 2.53 | 2.53 |
| 393.66 | 3.18 | 3.18 |
| 438.11 | 3.29 | 3.29 |
| 336.00 | 2.04 | 2.04 |
| 330.10 | 0.78 | 0.78 |
| 335.11 | 1.76 | 1.76 |
| 285.10 | 0.88 | 0.88 |
| 292.12 | 0.61 | 0.61 |
| 283.11 | 0.44 | 0.44 |
| 281.14 | 1.05 | 1.05 |
| 335.11 | 1.76 | 1.76 |
| 346.01 | 1.50 | 1.50 |
| 312.11 | 0.65 | 0.65 |
| 301.56 | 1.39 | 1.39 |
| 267.11 | 0.74 | 0.74 |
| 285.10 | 0.88 | 0.88 |
| 290.11 | -1.12 | -1.12 |