Basic Information
ID: ALA2444934
Type: Binding
Description: Inhibition of human DGAT-1 expressed in insect Sf9 cell microsomes using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA as substrate after 2 hrs
Organism: Homo sapiens
Cell type: Sf9
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA2444934
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 502.49 | 5.18 | 5.18 |
| 495.48 | 3.09 | 3.09 |
| 489.45 | 4.29 | 4.29 |
| 570.96 | 6.02 | 6.02 |
| 481.48 | 3.72 | 3.72 |
| 497.47 | 2.96 | 2.96 |
| 495.50 | 4.11 | 4.11 |
| 509.53 | 4.50 | 4.50 |
| 531.48 | 4.36 | 4.36 |
| 496.49 | 3.61 | 3.61 |
| 510.52 | 4.00 | 4.00 |
| 510.52 | 3.86 | 3.86 |
| 510.52 | 3.86 | 3.86 |
| 510.52 | 4.00 | 4.00 |
| 536.56 | 4.53 | 4.53 |
| 578.98 | 5.31 | 5.31 |
| 480.49 | 3.39 | 3.39 |
| 520.56 | 4.17 | 4.17 |
| 546.53 | 4.43 | 4.43 |
| 509.53 | 3.57 | 3.57 |
| 535.57 | 4.11 | 4.11 |
| 578.00 | 5.34 | 5.34 |
| 592.02 | 5.73 | 5.73 |
| 499.54 | 5.72 | 5.72 |
| 500.53 | 4.66 | 4.66 |
| 535.96 | 4.71 | 4.71 |
| 420.39 | 4.09 | 4.09 |
| 440.55 | 5.18 | 5.18 |
| 435.47 | 5.16 | 5.16 |
| 365.43 | 3.98 | 3.98 |
| 367.47 | 4.15 | 4.15 |
| 488.47 | 4.79 | 4.79 |