Basic Information
ID: ALA2445070
Type: Binding
Description: Inhibition of recombinant Leishmania donovani chagasi beta-carbonic anhydrase expressed in baculovirus infected insect Sf9 cells incubated for 15 mins prior to testing by stopped flow CO2 hydrase assay
Organism: Leishmania donovani chagasi
Cell type: Sf9
Activity Charts
Bioactivity
Activity Types for Assay ALA2445070
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 200.26 | -0.16 | -0.16 |
| 265.30 | 0.45 | 0.45 |
| 285.73 | -0.78 | -0.78 |
| 355.44 | 0.44 | 0.44 |
| 341.41 | 0.39 | 0.39 |
| 327.39 | 0.72 | 0.72 |
| 335.39 | -0.43 | -0.43 |
| 201.20 | 0.03 | 0.03 |
| 201.25 | -0.13 | -0.13 |
| 187.22 | -0.17 | -0.17 |
| 194.24 | -1.39 | -1.39 |
| 180.21 | -1.23 | -1.23 |
| 172.21 | -0.08 | -0.08 |
| 305.16 | 0.29 | 0.29 |
| 258.32 | 1.34 | 1.34 |
| 251.10 | 0.68 | 0.68 |
| 190.20 | 0.06 | 0.06 |
| 236.28 | -1.42 | -1.42 |
| 222.25 | -0.86 | -0.86 |
| 319.29 | -0.42 | -0.42 |
| 186.24 | -0.21 | -0.21 |
| 206.65 | 0.57 | 0.57 |
| 172.21 | -0.08 | -0.08 |
| 341.43 | 0.56 | 0.56 |
| 297.75 | -0.35 | -0.35 |
| 171.22 | 0.64 | 0.64 |
| 381.38 | 3.51 | 3.51 |
| 212.23 | 0.62 | 0.62 |
| 314.37 | 2.96 | 2.96 |
| 320.38 | -0.01 | -0.01 |
| 385.85 | 2.27 | 2.27 |
| 183.19 | 0.12 | 0.12 |
| 290.37 | 0.26 | 0.26 |
| 324.45 | 0.61 | 0.61 |
| 383.52 | 0.09 | 0.09 |
| 339.37 | -0.40 | -0.40 |
| 173.19 | 0.04 | 0.04 |
| 191.24 | 0.20 | 0.20 |
| 320.36 | 1.68 | 1.68 |
| 399.26 | 2.44 | 2.44 |
| 358.25 | 2.74 | 2.74 |
| 327.82 | 3.03 | 3.03 |
| 273.39 | 2.37 | 2.37 |
| 415.45 | 0.26 | 0.26 |
| 279.35 | 1.98 | 1.98 |
| 313.80 | 2.64 | 2.64 |
| 309.38 | 1.99 | 1.99 |
| 236.27 | -1.02 | -1.02 |
| 242.08 | 1.35 | 1.35 |
| 297.34 | 2.12 | 2.12 |