Basic Information
ID: ALA2445823
Type: Binding
Description: Inhibition of full-length huntingtin Q138 mutant (unknown origin) expressed in human T-RexTM-293 cells co-expressing CRE-Luc assessed as decrease of CREB-mediated transcription after 72 hrs by luciferase reporter gene based luminescence assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2445823
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 342.32 | 2.95 | 2.95 |
| 395.18 | 2.44 | 2.44 |
| 313.28 | 2.33 | 2.33 |
| 301.27 | 2.27 | 2.27 |
| 327.31 | 2.64 | 2.64 |
| 334.32 | 1.98 | 1.98 |
| 331.30 | 1.26 | 1.26 |
| 318.26 | 1.51 | 1.51 |
| 359.35 | 2.10 | 2.10 |
| 341.33 | 3.03 | 3.03 |
| 327.31 | 2.72 | 2.72 |
| 315.30 | 2.66 | 2.66 |
| 394.15 | 1.94 | 1.94 |
| 315.25 | 1.18 | 1.18 |
| 410.37 | 1.39 | 1.39 |
| 352.34 | 1.22 | 1.22 |
| 402.78 | 1.03 | 1.03 |
| 316.28 | 2.42 | 2.42 |