Basic Information
ID: ALA2446441
Type: Functional
Description: Inhibition of cholesterol synthesis in rat hepatocytes assessed as formation of cholesterol using [14C]mevalonolactone as substrate after 1 hr by liquid scintillation counting
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Hepatocyte
Target: Hepatocyte(ALA613362)
Document: ALA2439948
Inhibition of cholesterol synthesis in rat hepatocytes assessed as formation of cholesterol using [14C]mevalonolactone as substrate after 1 hr by liquid scintillation counting: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2446441
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 467.83 | 4.89 | 4.89 |
| 488.25 | 5.24 | 5.24 |
| 509.95 | 4.39 | 4.39 |
| 538.00 | 5.21 | 5.21 |
| 527.94 | 4.55 | 4.55 |
| 563.92 | 5.10 | 5.10 |
| 483.83 | 4.59 | 4.59 |
| 537.80 | 5.48 | 5.48 |
| 481.86 | 5.15 | 5.15 |