Basic Information
ID: ALA2446560
Type: Functional
Description: Antagonist activity at human histamine H3 receptor expressed in CHO cells assessed as inhibition of forskolin/R-alpha-methylhistamine-induced cAMP accumulation after 1.5 hrs by TR-FRET immunoassay
Organism: Homo sapiens
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA2446560
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 308.84 | 3.45 | 3.45 |
| 348.34 | 3.58 | 3.58 |
| 364.34 | 2.82 | 2.82 |
| 362.37 | 3.97 | 3.97 |
| 377.39 | 2.74 | 2.74 |
| 363.36 | 2.39 | 2.39 |
| 362.37 | 3.63 | 3.63 |
| 378.37 | 2.86 | 2.86 |
| 376.40 | 4.02 | 4.02 |
| 390.42 | 4.41 | 4.41 |
| 404.45 | 4.80 | 4.80 |
| 384.03 | 4.53 | 4.53 |
| 438.00 | 5.16 | 5.16 |
| 395.02 | 4.01 | 4.01 |
| 377.04 | 3.39 | 3.39 |
| 373.37 | 4.05 | 4.05 |
| 406.92 | 4.41 | 4.41 |
| 373.37 | 4.05 | 4.05 |