Assay Report Card

Basic Information

ID: ALA2446791

Type: Binding

Description: Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated at 10 uM for 10 mins before substrate addition by scintillation counting

Organism: Homo sapiens

Cell type: HEK293

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
330.473.693.69
330.473.693.69
329.483.663.66
443.634.634.63
387.523.383.38
458.603.683.68
542.765.665.66
502.704.184.18
416.562.702.70