Basic Information
ID: ALA2446792
Type: Binding
Description: Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for 10 mins before substrate addition by scintillation counting
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA2446792
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 330.47 | 3.69 | 3.69 |
| 330.47 | 3.69 | 3.69 |
| 329.48 | 3.66 | 3.66 |
| 443.63 | 4.63 | 4.63 |
| 387.52 | 3.38 | 3.38 |
| 458.60 | 3.68 | 3.68 |
| 542.76 | 5.66 | 5.66 |
| 502.70 | 4.18 | 4.18 |
| 416.56 | 2.70 | 2.70 |