Basic Information
ID: ALA2447105
Type: Functional
Description: Ratio of IC50 for vinblastine-resistant human HCT116/VM46 cells overexpressing P-gp to IC50 for vinblastine-sensitive human HCT116 cells by phosphatase assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HCT-116
Target: HCT-116(ALA394)
Document: ALA2440050
Ratio of IC50 for vinblastine-resistant human HCT116/VM46 cells overexpressing P-gp to IC50 for vinblastine-sensitive human HCT116 cells by phosphatase assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA2447105
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 810.99 | 3.99 | 3.99 |
| 919.13 | 4.97 | 4.97 |
| 955.17 | 5.72 | 5.72 |
| 985.19 | 5.73 | 5.73 |
| 969.19 | 5.77 | 5.77 |