Basic Information
ID: ALA2447428
Type: Binding
Description: Type-1 positive allosteric modulation of human alpha7 nAChR expressed in Xenopus oocytes assessed as maximum modulation of nicotine EC5 response by two-electrode voltage clamp method
Organism: Homo sapiens
Cell type: Oocyte
Activity Charts
Bioactivity
Activity Types for Assay ALA2447428
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 366.85 | 5.07 | 5.07 |
| 352.82 | 4.61 | 4.61 |
| 350.39 | 4.56 | 4.56 |
| 380.88 | 5.46 | 5.46 |
| 394.90 | 5.85 | 5.85 |
| 422.96 | 6.63 | 6.63 |
| 478.93 | 6.92 | 6.92 |
| 456.97 | 6.69 | 6.69 |
| 392.47 | 5.36 | 5.36 |
| 394.90 | 5.85 | 5.85 |
| 374.48 | 5.51 | 5.51 |
| 429.35 | 6.51 | 6.51 |
| 378.45 | 5.34 | 5.34 |
| 378.45 | 5.34 | 5.34 |
| 378.45 | 5.34 | 5.34 |
| 396.44 | 5.48 | 5.48 |
| 396.44 | 5.48 | 5.48 |
| 396.44 | 5.48 | 5.48 |
| 360.46 | 5.20 | 5.20 |
| 385.29 | 6.11 | 6.11 |
| 418.39 | 5.84 | 5.84 |
| 376.48 | 5.89 | 5.89 |
| 426.49 | 6.73 | 6.73 |
| 394.52 | 6.05 | 6.05 |
| 352.38 | 5.08 | 5.08 |
| 368.38 | 4.70 | 4.70 |
| 382.41 | 5.09 | 5.09 |