Basic Information
ID: ALA2448771
Type: ADME
Description: DNDI: Human CYP3A4 inhibition determined using 6b-hydroxylation of testosterone
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2448771
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 413.44 | 3.76 | 3.76 |
| 515.51 | 3.52 | 3.52 |
| 469.99 | 4.45 | 4.45 |
| 421.29 | 4.28 | 4.28 |
| 476.56 | 3.61 | 3.61 |
| 366.38 | 3.45 | 3.45 |
| 511.04 | 3.18 | 3.18 |
| 419.47 | 2.99 | 2.99 |
| 344.21 | 3.30 | 3.30 |
| 412.45 | 3.95 | 3.95 |
| 293.33 | 1.84 | 1.84 |
| 392.34 | 4.61 | 4.61 |
| 352.27 | 3.68 | 3.68 |
| 345.47 | 5.38 | 5.38 |
| 393.32 | 3.03 | 3.03 |
| 385.49 | 5.30 | 5.30 |
| 371.43 | 4.12 | 4.12 |
| 453.55 | 3.50 | 3.50 |
| 409.54 | 4.71 | 4.71 |
| 346.46 | 4.78 | 4.78 |
| 417.49 | 4.62 | 4.62 |
| 417.49 | 4.62 | 4.62 |
| 411.47 | 4.56 | 4.56 |
| 410.48 | 5.16 | 5.16 |
| 417.49 | 4.62 | 4.62 |
| 386.48 | 4.70 | 4.70 |
| 401.43 | 3.08 | 3.08 |
| 359.45 | 4.91 | 4.91 |
| 410.52 | 4.11 | 4.11 |
| 346.42 | 4.25 | 4.25 |
| 341.37 | 3.58 | 3.58 |
| 363.46 | 5.52 | 5.52 |
| 403.48 | 5.44 | 5.44 |
| 431.52 | 4.93 | 4.93 |
| 428.92 | 3.99 | 3.99 |
| 324.37 | 5.05 | 5.05 |
| 338.36 | 4.58 | 4.58 |
| 384.49 | 3.65 | 3.65 |
| 418.48 | 4.01 | 4.01 |
| 355.40 | 3.89 | 3.89 |
| 412.45 | 3.95 | 3.95 |
| 360.44 | 4.56 | 4.56 |
| 334.45 | 4.71 | 4.71 |
| 374.41 | 3.99 | 3.99 |
| 348.43 | 4.24 | 4.24 |
| 352.44 | 4.85 | 4.85 |
| 374.47 | 3.85 | 3.85 |
| 363.39 | 3.32 | 3.32 |
| 402.52 | 5.45 | 5.45 |
| 313.35 | 4.38 | 4.38 |
| 412.45 | 3.95 | 3.95 |