Basic Information
ID: ALA2448774
Type: ADME
Description: DNDI: Human CYP3A4 inhibition at 10 uM determined using 6b-hydroxylation of testosterone
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA2448774
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.34 | 4.61 | 4.61 |
| 346.42 | 4.25 | 4.25 |
| 341.37 | 3.58 | 3.58 |
| 431.52 | 4.93 | 4.93 |
| 428.92 | 3.99 | 3.99 |
| 384.49 | 3.65 | 3.65 |
| 418.48 | 4.01 | 4.01 |
| 355.40 | 3.89 | 3.89 |
| 412.45 | 3.95 | 3.95 |
| 360.44 | 4.56 | 4.56 |
| 334.45 | 4.71 | 4.71 |
| 348.43 | 4.24 | 4.24 |
| 363.39 | 3.32 | 3.32 |
| 402.52 | 5.45 | 5.45 |
| 313.35 | 4.38 | 4.38 |
| 412.45 | 3.95 | 3.95 |