Basic Information
ID: ALA3074361
Type: Binding
Description: Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min
Format: BAO_0000019
Organism: Hepatitis C virus genotype 1
Target: Hepatitis C virus NS5B RNA-dependent RNA polymerase(ALA5375)
Document: ALA3045038
Inhibition of Hepatitis C virus genotype 1 NS5B polymerases lacking C-terminal 47 amino acid residues expressed in Escherichia coli after 60 min: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3074361
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 567.09 | 8.81 | 8.81 |
| 682.19 | 8.54 | 8.54 |
| 571.50 | 9.46 | 9.46 |
| 567.09 | 8.81 | 8.81 |
| 581.07 | 8.50 | 8.50 |
| 537.06 | 8.81 | 8.81 |
| 670.21 | 9.74 | 9.74 |
| 608.14 | 8.51 | 8.51 |
| 537.06 | 8.81 | 8.81 |
| 570.61 | 9.17 | 9.17 |
| 612.10 | 8.30 | 8.30 |
| 551.09 | 9.11 | 9.11 |
| 580.08 | 7.91 | 7.91 |
| 562.07 | 8.68 | 8.68 |
| 532.64 | 8.16 | 8.16 |
| 520.60 | 8.29 | 8.29 |
| 571.50 | 9.46 | 9.46 |
| 542.04 | 8.10 | 8.10 |
| 616.14 | 7.45 | 7.45 |
| 558.10 | 8.57 | 8.57 |
| 640.16 | 9.09 | 9.09 |
| 640.16 | 9.08 | 9.08 |
| 642.13 | 7.67 | 7.67 |
| 626.13 | 8.65 | 8.65 |
| 666.19 | 9.57 | 9.57 |
| 644.19 | 8.06 | 8.06 |
| 579.10 | 9.01 | 9.01 |
| 580.13 | 8.87 | 8.87 |
| 538.05 | 8.20 | 8.20 |
| 537.06 | 8.81 | 8.81 |
| 558.10 | 8.57 | 8.57 |
| 594.11 | 8.76 | 8.76 |
| 581.07 | 8.50 | 8.50 |
| 562.07 | 8.68 | 8.68 |
| 594.11 | 8.17 | 8.17 |
| 608.14 | 8.51 | 8.51 |
| 668.16 | 8.42 | 8.42 |
| 626.13 | 8.93 | 8.93 |
| 640.16 | 9.32 | 9.32 |
| 538.05 | 8.20 | 8.20 |
| 538.05 | 8.20 | 8.20 |
| 654.18 | 9.56 | 9.56 |
| 654.18 | 9.71 | 9.71 |
| 638.14 | 9.07 | 9.07 |
| 641.14 | 9.04 | 9.04 |
| 520.60 | 8.29 | 8.29 |
| 571.05 | 8.04 | 8.04 |
| 640.11 | 8.22 | 8.22 |
| 598.07 | 8.04 | 8.04 |