Basic Information
ID: ALA3074524
Type: Binding
Description: Antagonist activity at ETA receptor in Sprague-Dawley Rattus norvegicus (rat) thoracic aortic ring assessed as inhibition of ET1-induced thoracic aortic ring contraction at 10 uM after 30 min relative to control
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Activity Charts
Bioactivity
Activity Types for Assay ALA3074524
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 610.71 | 0.83 | 0.83 |
| 282.30 | 4.02 | 4.02 |
| 220.22 | 2.84 | 2.84 |
| 234.25 | 3.23 | 3.23 |
| 248.28 | 3.62 | 3.62 |
| 262.30 | 4.01 | 4.01 |
| 308.33 | 4.53 | 4.53 |
| 326.35 | 4.21 | 4.21 |
| 346.77 | 4.55 | 4.55 |
| 346.77 | 4.55 | 4.55 |
| 289.33 | 2.91 | 2.91 |
| 340.36 | 4.02 | 4.02 |
| 324.29 | 3.55 | 3.55 |
| 326.30 | 3.64 | 3.64 |
| 354.36 | 4.42 | 4.42 |