Assay Report Card

Basic Information

ID: ALA3074572

Type: Binding

Description: Agonist activity at Homo sapiens (human) LXRalpha expressed in HepG2 cells assessed as transactivation of CYP7A1 gene expression at 100 nM after 48 hr by luciferase reporter gene assay relative to vehicle-treated control

Organism: Homo sapiens

Cell type: HepG2

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
481.344.764.76
368.431.311.31
352.432.342.34