Basic Information
ID: ALA3075308
Type: Binding
Description: Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 100 nM after 48 hr by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Bile acid receptor FXR(ALA2047)
Document: ALA3046494
Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 100 nM after 48 hr by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3075308
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 368.43 | 1.31 | 1.31 |
| 352.43 | 2.34 | 2.34 |