Basic Information
ID: ALA3075309
Type: Binding
Description: Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 1 uM after 48 hr by luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HepG2
Target: Bile acid receptor FXR(ALA2047)
Document: ALA3046494
Agonist activity at Homo sapiens (human) FXR ligand binding domain expressed in HepG2 cells assessed as transactivation of SHP gene expression at 1 uM after 48 hr by luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3075309
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.58 | 4.48 | 4.48 |
| 368.43 | 1.31 | 1.31 |
| 352.43 | 2.34 | 2.34 |