Basic Information
ID: ALA3076710
Type: Binding
Description: Antagonist activity at AT1 receptor in Rattus norvegicus (rat) adrenal cortex membrane
Format: BAO_0000221
Organism: Rattus norvegicus
Tissue: Adrenal cortex
Subcellular Fraction: Membrane
Target: Angiotensin II receptor (AT-1) type-1(ALA2094250)
Document: ALA3045622
Antagonist activity at AT1 receptor in Rattus norvegicus (rat) adrenal cortex membrane: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3076710
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 425.50 | 4.37 | 4.37 |
| 401.47 | 4.89 | 4.89 |
| 515.62 | 5.48 | 5.48 |
| 453.55 | 4.46 | 4.46 |
| 411.47 | 3.98 | 3.98 |
| 397.44 | 3.59 | 3.59 |
| 439.52 | 3.97 | 3.97 |
| 409.45 | 3.91 | 3.91 |
| 550.07 | 6.14 | 6.14 |
| 507.62 | 5.49 | 5.49 |
| 594.52 | 6.25 | 6.25 |
| 533.61 | 5.62 | 5.62 |
| 560.62 | 5.39 | 5.39 |
| 530.64 | 5.07 | 5.07 |
| 587.68 | 5.66 | 5.66 |
| 559.63 | 5.18 | 5.18 |
| 529.60 | 5.12 | 5.12 |
| 509.61 | 5.12 | 5.12 |
| 483.53 | 4.05 | 4.05 |
| 469.51 | 3.96 | 3.96 |
| 468.52 | 3.36 | 3.36 |
| 496.58 | 3.97 | 3.97 |
| 482.55 | 3.58 | 3.58 |
| 468.52 | 3.19 | 3.19 |
| 480.53 | 3.50 | 3.50 |
| 524.63 | 4.75 | 4.75 |
| 496.58 | 3.97 | 3.97 |
| 621.75 | 4.74 | 4.74 |
| 593.69 | 3.96 | 3.96 |
| 524.63 | 4.79 | 4.79 |
| 544.62 | 5.52 | 5.52 |
| 558.65 | 5.54 | 5.54 |
| 620.72 | 7.24 | 7.24 |