Basic Information
ID: ALA3076794
Type: Functional
Description: Anti-inflammatory activity in Homo sapiens (human) THP1 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 30 min prior to LPS-challenge measured after 24 hr by ELISA relative to control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: THP-1
Target: THP-1(ALA614245)
Document: ALA3046943
Anti-inflammatory activity in Homo sapiens (human) THP1 cells assessed as inhibition of LPS-induced IL6 production at 10 uM incubated for 30 min prior to LPS-challenge measured after 24 hr by ELISA relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3076794
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 444.79 | 5.42 | 5.42 |
| 384.43 | 4.87 | 4.87 |
| 370.40 | 4.36 | 4.36 |
| 181.14 | 1.81 | 1.81 |
| 199.59 | 3.17 | 3.17 |
| 223.23 | 1.88 | 1.88 |
| 426.35 | 4.65 | 4.65 |
| 426.35 | 4.65 | 4.65 |
| 410.35 | 4.77 | 4.77 |
| 410.35 | 4.77 | 4.77 |
| 360.34 | 3.89 | 3.89 |
| 394.78 | 4.54 | 4.54 |
| 374.37 | 4.19 | 4.19 |