Basic Information
ID: ALA3082114
Type: Binding
Description: Inhibition of carboxylesterase in Fischer 344 Rattus norvegicus (rat) liver microsomes using p-nitrophenyl acetate as substrate incubated for 5 min prior to substrate addition measured for 2 min by spectrophotometric analysis
Organism: Rattus norvegicus
Strain: Fischer 344
Tissue: Liver
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3082114
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 256.33 | 4.21 | 4.21 |
| 228.28 | 3.43 | 3.43 |
| 284.39 | 4.99 | 4.99 |
| 312.44 | 5.77 | 5.77 |
| 362.45 | 3.57 | 3.57 |
| 334.40 | 2.79 | 2.79 |
| 306.35 | 2.00 | 2.00 |
| 278.29 | 1.22 | 1.22 |
| 248.27 | 3.09 | 3.09 |
| 298.28 | 0.89 | 0.89 |