Basic Information
ID: ALA3088429
Type: Binding
Description: Inhibition of human recombinant PDE10A using cAMP as substrate preincubated for 30 mins prior to substrate addition measured after 1 hr by IMAP TR-FRET analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3088429
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 388.43 | 3.73 | 3.73 |
| 444.45 | 5.88 | 5.88 |
| 302.34 | 4.49 | 4.49 |
| 405.48 | 4.46 | 4.46 |
| 349.39 | 3.24 | 3.24 |
| 418.48 | 3.95 | 3.95 |
| 401.43 | 3.21 | 3.21 |
| 415.45 | 3.22 | 3.22 |
| 399.45 | 4.37 | 4.37 |
| 415.45 | 3.60 | 3.60 |
| 414.47 | 3.13 | 3.13 |
| 429.48 | 3.99 | 3.99 |
| 415.45 | 3.34 | 3.34 |
| 428.45 | 2.65 | 2.65 |
| 442.48 | 3.04 | 3.04 |
| 457.53 | 4.36 | 4.36 |
| 511.50 | 4.91 | 4.91 |