Assay Report Card

Basic Information

ID: ALA3089316

Type: Binding

Description: Competitive inhibition of human NPP1 expressed in COS7 cells assessed as production of p-nitrophenol using pnp-TMP as the substrate preincubated at 25 to 100 uM for 3 mins before substrate addition measured after 15 mins by Dixon/Cornish Bowden method

Organism: Homo sapiens

Cell type: COS-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
587.28-0.20-0.20
507.31-0.32-0.32
501.03
501.03
547.13
569.92
569.92