Basic Information
ID: ALA3090350
Type: Binding
Description: Inhibition of human recombinant TTR Y78F mutant-mediated fibrillogenesis at 40 uM after 30 mins by turbidimetric assay relative to control
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3090350
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.36 | 4.83 | 4.83 |
| 300.44 | 5.60 | 5.60 |
| 184.11 | 1.21 | 1.21 |
| 244.26 | 3.68 | 3.68 |
| 281.23 | 4.15 | 4.15 |
| 296.15 | 4.36 | 4.36 |
| 250.20 | 3.04 | 3.04 |
| 228.25 | 2.97 | 2.97 |
| 323.99 | 5.38 | 5.38 |
| 283.11 | 4.06 | 4.06 |
| 234.20 | 3.33 | 3.33 |
| 776.87 | 4.56 | 4.56 |
| 747.83 | 5.23 | 5.23 |
| 376.10 | 3.64 | 3.64 |
| 299.22 | 4.29 | 4.29 |
| 315.68 | 4.80 | 4.80 |
| 360.13 | 4.91 | 4.91 |
| 407.13 | 4.75 | 4.75 |
| 268.19 | 3.17 | 3.17 |
| 284.64 | 3.69 | 3.69 |
| 329.10 | 3.80 | 3.80 |