Basic Information
ID: ALA3090716
Type: Functional
Description: Leishmanicidal activity against intracellular amastigote stage of Leishmania amazonensis MHOM/Br/79/Maria infected in mouse J774 cells assessed as reduction of parasite load after 48 hrs by resazurin dye-based fluorometric analysis
Organism: Leishmania amazonensis
Strain: MHOM/Br/79/Maria
Cell type: J774
Activity Charts
Bioactivity
Activity Types for Assay ALA3090716
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 407.58 | 5.68 | 5.68 |
| 307.76 | 3.02 | 3.02 |
| 280.27 | 1.19 | 1.19 |
| 334.40 | 4.19 | 4.19 |
| 286.36 | 3.28 | 3.28 |
| 273.32 | 2.36 | 2.36 |
| 291.31 | 2.50 | 2.50 |
| 290.37 | 3.10 | 3.10 |
| 289.40 | 3.26 | 3.26 |