Basic Information
ID: ALA3090823
Type: Binding
Description: Competitive inhibition of recombinant human DOT1L using adenosine/deazaadenosine as substrate and SAM cofactor
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3090823
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 384.42 | -1.44 | -1.44 |
| 392.15 | -0.77 | -0.77 |
| 294.32 | -1.41 | -1.41 |
| 340.41 | -0.89 | -0.89 |
| 539.68 | 2.85 | 2.85 |
| 457.49 | -0.07 | -0.07 |
| 499.57 | 1.05 | 1.05 |
| 458.54 | 1.57 | 1.57 |
| 460.52 | 1.40 | 1.40 |
| 473.56 | 0.65 | 0.65 |
| 459.53 | 0.97 | 0.97 |
| 445.51 | 0.58 | 0.58 |
| 473.56 | 1.36 | 1.36 |
| 493.98 | 1.63 | 1.63 |
| 527.53 | 1.99 | 1.99 |
| 540.67 | 2.25 | 2.25 |
| 554.70 | 2.71 | 2.71 |
| 398.45 | -0.98 | -0.98 |
| 549.37 | -0.58 | -0.58 |
| 462.33 | -0.07 | -0.07 |
| 618.58 | 3.61 | 3.61 |
| 562.72 | 3.32 | 3.32 |
| 512.62 | 1.47 | 1.47 |
| 538.70 | 2.91 | 2.91 |
| 536.68 | 2.83 | 2.83 |
| 538.70 | 2.91 | 2.91 |
| 515.64 | 2.27 | 2.27 |
| 558.64 | 2.49 | 2.49 |
| 521.32 | -1.43 | -1.43 |
| 535.34 | -1.04 | -1.04 |
| 322.37 | -0.63 | -0.63 |