Basic Information
ID: ALA3091162
Type: Binding
Description: Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contraction after 1 to 4 hrs
Format: BAO_0000357
Organism: Cavia porcellus
Strain: Dunkin-Hartley
Target: Muscarinic acetylcholine receptor M3(ALA5498)
Document: ALA3085673
Antagonist activity at M3 receptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of methacholine-induced airway smooth muscle contraction after 1 to 4 hrs: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3091162
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.63 | 5.39 | 5.39 |
| 453.67 | 5.52 | 5.52 |
| 449.66 | 5.70 | 5.70 |
| 475.65 | 6.14 | 6.14 |
| 373.52 | 2.85 | 2.85 |
| 467.61 | 5.14 | 5.14 |
| 440.56 | 3.99 | 3.99 |
| 454.59 | 4.30 | 4.30 |
| 450.60 | 4.40 | 4.40 |
| 451.59 | 3.79 | 3.79 |
| 451.59 | 3.79 | 3.79 |
| 486.04 | 4.45 | 4.45 |
| 486.04 | 4.45 | 4.45 |
| 447.60 | 5.71 | 5.71 |
| 474.63 | 5.62 | 5.62 |
| 473.64 | 6.22 | 6.22 |
| 473.64 | 6.22 | 6.22 |
| 474.63 | 5.62 | 5.62 |
| 420.62 | 5.61 | 5.61 |
| 440.67 | 5.98 | 5.98 |
| 455.06 | 6.26 | 6.26 |
| 436.62 | 5.44 | 5.44 |
| 450.64 | 5.58 | 5.58 |
| 450.64 | 5.83 | 5.83 |