Basic Information
ID: ALA3095473
Type: Binding
Description: Antagonist activity at human alpha7 nAChR expressed in Xenopus oocytes assessed as inhibition of acetylcholine-induced effect at 1 uM incubated for 12 secs followed by compound washout measured after 181 secs by two-electrode voltage clamp technique
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3095473
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 307.40 | 2.43 | 2.43 |
| 307.40 | 2.43 | 2.43 |
| 296.37 | 1.55 | 1.55 |
| 244.34 | 1.30 | 1.30 |
| 322.43 | 0.70 | 0.70 |
| 249.31 | 0.59 | 0.59 |
| 245.33 | 0.69 | 0.69 |
| 245.33 | 0.69 | 0.69 |
| 288.35 | 1.03 | 1.03 |
| 294.40 | 2.45 | 2.45 |
| 258.37 | 1.69 | 1.69 |
| 259.35 | 1.08 | 1.08 |
| 270.38 | 1.86 | 1.86 |
| 256.35 | 1.77 | 1.77 |
| 290.79 | 2.42 | 2.42 |
| 274.34 | 1.91 | 1.91 |
| 286.38 | 1.78 | 1.78 |
| 262.38 | 1.83 | 1.83 |
| 257.34 | 1.16 | 1.16 |
| 257.34 | 1.16 | 1.16 |
| 300.36 | 1.50 | 1.50 |
| 254.33 | 1.11 | 1.11 |
| 314.39 | 1.12 | 1.12 |
| 318.80 | 1.77 | 1.77 |
| 298.34 | 0.83 | 0.83 |